Afflovest Clinicial Support & Evidence
International Biophysics is committed to providing clinical evidence to support our products. View a collection of recently completed clinical studies on HFCWO therapy vests and their impact on lung function scores, spirometry measurements, EMI output and noise production.
Reduction in Antibiotic Use, Emergency Visits and Hospitalizations in COPD/Bronchiectasis Patients after Initiating AffloVest® HFCWO Therapy
In a recent study, COPD and bronchiectasis patients using AffloVest high frequency chest wall oscillation therapy showed reduced hospitalizations for respiratory causes and better overall respiratory health.
Clinician’s Data Analysis: Lung function improvement maintained over 16 to 24 months with use of AffloVest™
Ongoing data collected for this clinician paper was collected from the same five patients after 16 to 24 months of treatment using the AffloVest. The data collected on the five AffloVest patients shows that lung improvement overall was maintained over that total time period.
An evidence-based study of adolescents with Cystic Fibrosis demonstrated that AffloVest®
In the following case study, five adolescent patients used the AffloVest by International Biophysics for 3–5 months each and saw increased Pulmonary Function Test (PFT) scores. The objective of the study was to measure lung function scores before and after use to determine efficacy.
A Clinician’s Percpective on PFT Score Data
Read an evidence-based study conducted by Michael Cooper of 25 adolescents with cystic fibrosis, which demonstrated that the use of the AffloVest, by International Biophysics contributed to improved lung function scores.
Dr. O’Brien IRB 1 Page Summary
A brief 1 page summary of the findings of the Effect of High Frequency Chest Wall Oscillation Vests on Spirometry Measurements: An IRB Published Clinical Study
NTM Survey – Bronchiectasis and Airway Clearance Therapy
An exploration of Bronchiectasis and airway clearance therapy (ACT). NTM Info & Research survey results reveal patient and physician behaviors related to ACT adherence.

Effect of High Frequency Chest Wall Oscillation Vests on Spirometry Measurements
Dr. Thomas O’Brien performed this study to investigate the effects of the short-term application of motor and compressor-based HFCWO vests on the spirometry parameters and to assess if there were significant differences between the two device types.
Clinical Summary of COPD and Bronchiectasis
According to the COPD Foundation there are 24 million persons in the USA with COPD and there are 8 million estimated with Bronchiectasis. Bronchiectasis is typically under-diagnosed due to several possible reasons.
HFCWO Therapy Vest Noise Study
An independent lab study measuring the Peak Audible Noise Levels of the 5 current HFCWO vests on the market.
Peak Magnetic Field Comparison of AffloVest and Monarch Vests
An independent lab study performed to measure the Peak Magnetic Field of the AffloVest and Monarch HFCWO therapy vests.